The birth of a Revolution
Few technologies have significantly impacted mass cytometry in the ever-evolving landscape of cellular analysis. This revolutionary technique has transformed our ability to peer into the intricate world of cells, offering unprecedented insights into their complexity and behavior.
The story of mass cytometry begins, like many scientific breakthroughs, with a moment of inspiration. Legend has it that Scott Tanner, a professor at the University of Toronto, having the idea of using the precision of mass spectrometry to analyze cells. This seemingly simple idea would lead to a paradigm shift in single-cell analysis. In 2004, he founded DVS sciences, acquired by Fluidigm in 2014, renamed later Standard BioTools in 2022, reaching 200 millions revenues in 2022.
In 2009, Tanner and his team, including Dmitry Bandura, Vladimir Baranov, and Olga Ornatsky, published their groundbreaking paper introducing mass cytometry to the world (Bandura et al., 2009). Their technique combined the cellular analysis capabilities of flow cytometry with the high-resolution mass analysis of inductively coupled plasma mass spectrometry (ICP-MS).
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